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Colour in cultured pearls has many causes, namely organic pigments and the water reservoir where the pearl shell is grown (sea water or freshwater) that has different manganese (Mn) concentrations with impact on nacre's colours. The mollusc species is, of course, one of the most important factors...Mother-of-pearl has been used since pre-historic times for adornment. In the modern ages, it was also artistically used in marquetry, gaming chips, devotional artefacts, as a bead for the cultured pearl industry but also in the button industry, being rather popular before plastics came into actio...During Christopher Columbus’s third (1498) and fourth (1502) voyages to the New World, he repeatedly encountered native people adorned with natural pearls.